The rise in the number of adults taking medication to combat depression in Scotland is "extremely worrying", a Labour health spokesman said.
Dr Richard Simpson expressed concern after health service statistics revealed that one in 10 adults in the country take anti-depressants on a daily basis.
His concern was echoed by Billy Watson, chief executive of the Scottish Association for Mental Health (SAMH), who called for a review of current treatments available for doctors to prescribe to patients suffering from depression.
Mr Watson said: "We all know these are difficult times and the recession is having a widely reported impact on the mental health of the nation. However, SAMH is concerned that one in 10 of the adult population in Scotland is now taking anti-depressants regularly.
"SAMH believes that the best way to support people with mental health problems is to provide prompt access to a wide range of treatments, including talking therapies and exercise. But unfortunately, people are still being prescribed anti-depressants because other options are not routinely available to GPs."
A total of 4.01 million anti-depressants were prescribed in Scotland in 2008-09, up 178,650 on the previous year.